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Article

The impact of functional LIG4 polymorphism on platinum-based chemotherapy response and survival in non-small cell lung cancer.

Medical oncology (Northwood, London, England) - 1 May 2014

Jiang You-Hua, Xu Xiao-Ling, Ruan Hai-Hong, Xu Wei-Zhen, Li Dan, Feng Jian-Guo, Han Qian-Bo, Mao Wei-Min

Abstract excerpt

DNA repair capacity is correlated with the sensitivity of cancer cells toward platinum-based chemotherapy. The aim of this study was to investigate whether single-nucleotide polymorphisms (SNPs) in DNA repair genes NBS1, LIG4, and RAD51 were correlated with tumor response in advanced non-small ce...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24722796
DOI: 10.1007/s12032-014-0959-7

Genes

LIG4
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24722796-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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