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Article

Lipoprotein-associated phospholipase A2 regulates macrophage apoptosis via the Akt and caspase-7 pathways.

Journal of atherosclerosis and thrombosis - 1 Jan 2014

Maeda Toshinaga, Takeuchi Keisuke, Xiaoling Pang, P Zankov Dimitar, Takashima Naoyuki, Fujiyoshi Akira, Kadowaki Takashi, Miura Katsuyuki, Ueshima Hirotsugu, Ogita Hisakazu

Abstract excerpt

AIM: Mutations in lipoprotein-associated phospholipase A2 (Lp-PLA2) are related to atherosclerosis. However, the molecular effects of Lp-PLA2 on atherosclerosis have not been fully investigated. Therefore, this study attempted to elucidate this issue. METHODS: Monocytes were isolated from randoml...

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Identifiers

PMID: 24717759
DOI: 10.5551/jat.21386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-24717759-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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