Article
Genetic analysis of SNPs in CACNA1C and ANK3 gene with schizophrenia: A comprehensive meta-analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2015
Nie Fayi, Wang Xiaoli, Zhao Panpan, Yang Hao, Zhu Wenhua, Zhao Yaling, Chen Bo, Valenzuela Robert K, Zhang Rui, Gallitano Amelia L, Ma Jie
Abstract excerpt
Recently, genome-wide association studies (GWAS), meta-analyses, and replication studies focusing on bipolar disorder (BD) have implicated the α-1C subunit of the L-type voltage-dependent calcium channel (CACNA1C) and ankyrin 3 (ANK3) genes in BD. Based on the hypothesis that both schizophrenia (SZ) and BD may share some common genetic risk factors, we investigated the association of CACNA1C and ANK3 with SZ...
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