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Article

Simultaneous copy number losses within multiple subtelomeric regions in early-onset type 2 diabetes mellitus.

PloS one - 1 Jan 2014

Kodama Shinjiro, Yamada Tetsuya, Imai Junta, Sawada Shojiro, Takahashi Kei, Tsukita Sohei, Kaneko Keizo, Uno Kenji, Ishigaki Yasushi, Oka Yoshitomo, Katagiri Hideki

Abstract excerpt

Genetic factors play very important roles in the onset and progression of type 2 diabetes mellitus (T2DM). However, the genetic factors correlating with T2DM onset have not as yet been fully clarified. We previously found that copy number losses in the subtelomeric region on chromosome 4p16.3 were detected in early-onset Japanese T2DM patients (onset age <35 years) at a high frequency. Herein, we additionally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24709989
DOI: 10.1371/journal.pone.0088602
PMCID: PMC3977841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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