Article
Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma.
Scientific reports - 17 Jan 2018
Sato Seijiro, Nagahashi Masayuki, Koike Terumoto, Ichikawa Hiroshi, Shimada Yoshifumi, Watanabe Satoshi, Kikuchi Toshiaki, Takada Kazuki, Nakanishi Ryota, Oki Eiji, Okamoto Tatsuro, Akazawa Kouhei, Lyle Stephen, Ling Yiwei, Takabe Kazuaki, Okuda Shujiro, Wakai Toshifumi, Tsuchida Masanori
Abstract excerpt
Next-generation sequencing (NGS) has enabled comprehensive detection of genomic alterations in lung cancer. Ethnic differences may play a critical role in the efficacy of targeted therapies. The aim of this study was to identify and compare genomic alterations of lung adenocarcinoma between Japanese patients and the Cancer Genome Atlas (TCGA), which majority of patients are from the US. We also aimed to examine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.