Article
Detecting Somatic Mutations for Well-Differentiated Pancreatic Neuroendocrine Tumors in Endoscopic Ultrasound-Guided Fine Needle Aspiration with Next-Generation Sequencing.
Annals of surgical oncology - 1 Nov 2023
Ghabi Elie M, Habib Joseph R, Shoucair Sami, Javed Ammar A, Sham Jonathan, Burns William R, Cameron John L, Ali Syed Z, Shin Eun Ji, Arcidiacono Paolo Giorgio, Doglioni Claudio, Falconi Massimo, Yu Jun, Partelli Stefano, He Jin
Abstract excerpt
BACKGROUND: Pancreatic neuroendocrine tumors (PanNETs) exhibit heterogenous behavior, whereby some small tumors are aggressive with a propensity for metastasis. Detection of somatic mutations associated with aggressive biology may help with patient stratification and surgical decision-making in patients with well-differentiated PanNETs. Using next-generation sequencing (NGS), we investigated the feasibility of...
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