Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting tropomyosin-receptor kinase fused gene in cancer.

Anticancer research - 1 Apr 2014

Chen Yun, Tseng Sheng-Hong

Abstract excerpt

Tropomyosin-receptor kinase fused gene (TRK-fused gene, TFG) encodes a protein which is a conserved regulator of protein secretion that localizes in the endoplasmic reticulum exit sites and controls the export of materials from the endoplasmic reticulum. It is important for intracellular trafficking of protein secretion. TFG belongs to the systems which control cell size, and is involved in regulatory mechanisms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Cell Transformation, Neoplastic
Share to Intracellular Space

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Targeted Therapy

Share to Oncogene Proteins

Share to Oncogene Proteins, Fusion

Share to Protein Kinase Inhibitors

Share to Protein Transport

Source

Identifiers

PMID: 24692687

Genes

TFG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting tropomyosin-receptor kinase fused gene in cancer.PMID 24692687Read ↗

Roles of TrkC Signaling in the Regulation of Tumorigenicity and Metastasis of CancerSemantic proximity Read ↗

Research Advances in the Role of the Tropomyosin Family in CancerSemantic proximity Read ↗

Targeting Cellular Trafficking of Fibroblast Growth Factor Receptors as a Strategy for Selective Cancer TreatmentSemantic proximity Read ↗

TFG-Related Neurologic Disorders: New Insights Into Relationships Between Endoplasmic Reticulum and Neurodegeneration.Semantic proximity Read ↗

Biological role and expression of translationally controlled tumor protein (TCTP) in tumorigenesis and development and its potential for targeted tumor therapySemantic proximity Read ↗

Targeting Gas6/TAM in cancer cells and tumor microenvironmentSemantic proximity Read ↗

Golgi Retention and Oncogenic Signaling of KIT Tyrosine Kinase in Gastrointestinal Stromal Tumor.Semantic proximity Read ↗

Evidence of TRK-Fused Gene (TFG1) function in the ubiquitin-proteasome system.Semantic proximity Read ↗

Novel functions of thyroid hormone receptor mutants: beyond nucleus-initiated transcription.Semantic proximity Read ↗

RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells.Semantic proximity Read ↗

TrkBT1 Induces Liver Metastasis of Pancreatic Cancer Cells by Sequestering Rho GDP Dissociation Inhibitor and Promoting RhoA ActivationSemantic proximity Read ↗

GOLGA2/GM130, cis-Golgi Matrix Protein, is a Novel Target of Anticancer Gene TherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.