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Article

The effects of ABCG5/G8 polymorphisms on HDL-cholesterol concentrations depend on ABCA1 genetic variants in the Boston Puerto Rican Health Study.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Oct 2010

Junyent M, Tucker K L, Smith C E, Lane J M, Mattei J, Lai C Q, Parnell L D, Ordovas J M

Abstract excerpt

BACKGROUND AND AIMS: ATP-binding cassette transporters G5/G8 (ABCG5/G8) are associated with HDL-C concentrations. To assess whether the effect of ABCG5/G8 genetic variants on HDL-C concentrations is dependent on ATP-binding cassette transporters A1 (ABCA1), we studied potential interactions between single nucleotide polymorphisms (SNPs) at ABCG5/G8 (i7892T > C, 5U145A > C, T54CA > G, T400KC > A) and ABCA1...

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Source

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Identifiers

PMID: 19692220
DOI: 10.1016/j.numecd.2009.05.005
PMCID: PMC4038034

Genes

ABCA1
ABCG5
ABCG8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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