Article
Monocytes from pregnant women with pre-eclampsia are polarized to a M1 phenotype.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Jul 2014
Medeiros Leonardo T L, Peraçoli José C, Bannwart-Castro Camila F, Romão Mariana, Weel Ingrid C, Golim Marjorie A, de Oliveira Leandro G, Kurokawa Cilmery S, Medeiros Borges Vera T, Peraçoli Maria T S
Abstract excerpt
PROBLEM: This study evaluated whether the monocyte inflammatory state in pre-eclampsia (PE) might be associated with polarization to either M1 classically or M2 alternatively activated monocyte subsets. METHOD OF STUDY: Eighty-five women with (PE) and 52 normotensive (NT) pregnant women matched for gestational age were included. Expression of surface receptors characteristic of M1, such as Toll-like receptor...
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