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Article

Emerging patterns and implications of HIV-1 integrase inhibitor resistance

18 Oct 2012

Abstract excerpt

PURPOSE OF REVIEW: This review highlights recent data on the pathways of resistance that impact the clinical activity of first-generation and second-generation integrase inhibitors. RECENT FINDINGS: Raltegravir (RAL) and elvitegravir (EVG) are highly efficacious in first-line antiretroviral therapy, with small numbers of virological failures observed in clinical trials. Durable activity in treatment-experienced...

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Identifiers

PMID: 23086187
DOI: 10.1097/qco.0b013e32835a1de7

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