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Article

Advanced tools for BRCA1/2 mutational screening: comparison between two methods for large genomic rearrangements (LGRs) detection.

Clinical chemistry and laboratory medicine - 1 Aug 2014

Concolino Paola, Mello Enrica, Minucci Angelo, Santonocito Concetta, Scambia Giovanni, Giardina Bruno, Capoluongo Ettore

Abstract excerpt

BACKGROUND: Currently, multiplex ligation-dependent probe amplification (MLPA) is the most commonly used technique for the detection of large genomic rearrangements (LGRs) in the BRCA1/2 genes. However, a very fast assay, the BRCA1/2 multiplex amplicon quantification (MAQ), has been recently developed by Multiplicom. METHODS: As no data regarding the application of MAQ method to BRCA1/2 genes are available in...

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PMID: 24670361
DOI: 10.1515/cclm-2013-1114

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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