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Cerebrospinal Fluid Mitochondrial DNA

25 Mar 2014

Abstract excerpt

Danger-associated molecular patterns (DAMPs) are nuclear or cytoplasmic proteins that are released from the injured tissues and activate the innate immune system. Mitochondrial DNA (mtDNA) is a novel DAMP that is released into the extracellular milieu subsequent to cell death and injury. We hypothesized that cell death within the central nervous system in children with traumatic brain injury (TBI) would lead to...

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PMID: 24667615
DOI: 10.1097/shk.0000000000000160

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