Article
F4-related mutation and expression analysis of the aminopeptidase N gene in pigs.
Journal of animal science - 1 May 2014
Goetstouwers T, Van Poucke M, Nguyen V U, Melkebeek V, Coddens A, Deforce D, Cox E, Peelman L J
Abstract excerpt
Intestinal infections with F4 enterotoxigenic Escherichia coli (ETEC) are worldwide an important cause of diarrhea in neonatal and recently weaned pigs. Adherence of F4 ETEC to the small intestine by binding to specific receptors is mediated by F4 fimbriae. Porcine aminopeptidase N (ANPEP) was recently identified as a new F4 receptor. In this study, 7 coding mutations and 1 mutation in the 3' untranslated region...
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