Article
A genome-wide association study identifies two novel promising candidate genes affecting Escherichia coli F4ab/F4ac susceptibility in swine.
PloS one - 1 Jan 2012
Fu Wei-Xuan, Liu Yang, Lu Xin, Niu Xiao-Yan, Ding Xiang-Dong, Liu Jian-Feng, Zhang Qin
Abstract excerpt
Enterotoxigenic Escherichia coli (ETEC) expressing F4 fimbria is the major pathogenic bacteria causing diarrhoea in neonatal and post-weaning piglets. Previous studies have revealed that the susceptibility to ETEC F4ab/F4ac is an autosomal Mendelian dominant trait and the loci controlling the F4ab/F4ac receptor are located on SSC13q41, between markers SW207 and S0283. To pinpoint these loci and further validate...
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