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Article

Susceptibility towards enterotoxigenic Escherichia coli F4ac diarrhea is governed by the MUC13 gene in pigs.

PloS one - 1 Jan 2012

Ren Jun, Yan Xueming, Ai Huashui, Zhang Zhiyan, Huang Xiang, Ouyang Jing, Yang Ming, Yang Huaigu, Han Pengfei, Zeng Weihong, Chen Yijie, Guo Yuanmei, Xiao Shijun, Ding Nengshui, Huang Lusheng

Abstract excerpt

Enterotoxigenic Escherichia coli (ETEC) F4ac is a major determinant of diarrhea and mortality in neonatal and young pigs. Susceptibility to ETEC F4ac is governed by the intestinal receptor specific for the bacterium and is inherited as a monogenic dominant trait. To identify the receptor gene (F4acR), we first mapped the locus to a 7.8-cM region on pig chromosome 13 using a genome scan with 194 microsatellite...

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Identifiers

PMID: 22984528
DOI: 10.1371/journal.pone.0044573
PMCID: PMC3440394

Genes

MUC13
PTS

Provenance

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