Article
Epithelial function and dysfunction in asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Nov 2014
Loxham M, Davies D E, Blume C
Abstract excerpt
Asthma was previously defined as an allergic Th2-mediated inflammatory immune disorder. Recently, this paradigm has been challenged because not all pathological changes observed in the asthmatic airways are adequately explained simply as a result of Th2-mediated processes. Contemporary thought holds that asthma is a complex immune disorder involving innate as well as adaptive immune responses, with the clinical...
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