Article
Airway epithelial barrier function regulates the pathogenesis of allergic asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Jan 2014
Heijink I H, Nawijn M C, Hackett T-L
Abstract excerpt
The integrity of the airway epithelium in patients with asthma is often disrupted, with loss of epithelial cell-cell contacts. Airway epithelial barrier dysfunction may have important implications for asthma, because structural epithelial barrier function is tightly interwoven with the ability of the epithelium to regulate the immune system. We propose that changes at the airway epithelial barrier play a central...
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