Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CCCTC binding factor (CTCF)-dependent intragenic chromatin loop.

The Journal of biological chemistry - 2 May 2014

Sheng Jinghao, Luo Chi, Jiang Yuxiang, Hinds Philip W, Xu Zhengping, Hu Guo-fu

Abstract excerpt

Angiogenin (ANG) and ribonuclease 4 (RNASE4), two members of the secreted and vertebrate-specific ribonuclease superfamily, play important roles in cancers and neurodegenerative diseases. The ANG and RNASE4 genes share genetic regions with promoter activities, but the structure and regulation of these putative promotes are unknown. We have characterized the promoter regions, defined the transcription start site,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCCTC-Binding Factor
Share to Chromatin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Luciferases

Share to Ribonuclease, Pancreatic

Share to Ribonucleases

Share to RNA Polymerase II

Share to RNA Polymerase III

Share to Transcription Initiation Site

Source

Open in PubMed Open full text

Identifiers

PMID: 24659782
DOI: 10.1074/jbc.M114.551762
PMCID: PMC4007445

Genes

ANG
CTCF
RNASE4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription of angiogenin and ribonuclease 4 is regulated by RNA polymerase III elements and a CCCTC binding factor (CTCF)-dependent intragenic chromatin loop.PMID 24659782Read ↗

Tissue-Specific Epigenetics of Atherosclerosis-Related ANGPT and ANGPTL GenesSemantic proximity Read ↗

Three decades of research on angiogenin: a review and perspectiveSemantic proximity Read ↗

The angiogenins: An emerging family of ribonuclease related proteins with diverse cellular functionsSemantic proximity Read ↗

The Glucocorticoid Receptor Regulates the ANGPTL4 Gene in a CTCF-Mediated Chromatin Context in Human Hepatic CellsSemantic proximity Read ↗

Two genes, COL4A3 and COL4A4 coding for the human α3(IV) and α4(IV) collagen chains are arranged head‐to‐head on chromosome 2q361Semantic proximity Read ↗

Identification and characterization of the potential promoter regions of 1031 kinds of human genes.Semantic proximity Read ↗

Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization.Semantic proximity Read ↗

The collagenase gene promoter contains a TPA and oncogene‐responsive unit encompassing the PEA3 and AP‐1 binding sites.Semantic proximity Read ↗

Mapping of the Human <i>RNASEL</i> Promoter and Expression in Cancer and Normal CellsSemantic proximity Read ↗

Structure and organization of the human deoxyribonuclease II (DNase II) gene.Semantic proximity Read ↗

Characterization of an Evolutionarily Conserved Far-upstream Enhancer in the Human α2(I) Collagen (COL1A2) GeneSemantic proximity Read ↗

A proximal tissue-specific module and a distal negative regulatory module control apolipoprotein(a) gene transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.