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Article

A proximal tissue-specific module and a distal negative regulatory module control apolipoprotein(a) gene transcription.

The Biochemical journal - 1 Apr 2004

Negi Sarita, Singh Saurabh K, Pati Nirupma, Handa Vikas, Chauhan Ruchi, Pati Uttam

Abstract excerpt

The apo(a) [apolipoprotein(a)] gene is responsible for variations in plasma lipoprotein(a), high levels of which are a risk factor for atherosclerosis and myocardial infarction. The apo(a) promoter stimulates the expression of reporter genes in HepG2 cells, but not in HeLa cells. In the present s...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Regulatory Sequences, Nucleic Acid

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Source

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Identifiers

PMID: 14680477
DOI: 10.1042/BJ20030985
PMCID: PMC1224047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14680477-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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