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Article

TroX: a new method to learn about the genesis of aneuploidy from trisomic products of conception.

Bioinformatics (Oxford, England) - 15 Jul 2014

Kermany Amir R, Segurel Laure, Oliver Tiffany R, Przeworski Molly

Abstract excerpt

MOTIVATION: An estimated 10-30% of clinically recognized conceptions are aneuploid, leading to spontaneous miscarriages, in vitro fertilization failures and, when viable, severe developmental disabilities. With the ongoing reduction in the cost of genotyping and DNA sequencing, the use of high-density single nucleotide polymorphism (SNP) markers for clinical diagnosis of aneuploidy and biomedical research into...

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Identifiers

PMID: 24659032
DOI: 10.1093/bioinformatics/btu159
PMCID: PMC4080739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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