Article
Papillary renal cell carcinoma: A review of the current therapeutic landscape.
Critical reviews in oncology/hematology - 1 Oct 2015
Courthod Giulia, Tucci Marcello, Di Maio Massimo, Scagliotti Giorgio V
Abstract excerpt
Renal cell carcinoma (RCC) is the most common cancer of the kidney and accounts for 2-3% of all adult malignancies. Clear cell carcinoma represents the most common histologic subtype, while papillary Renal Cell Carcinoma (pRCC) accounts for 10-20% of all renal cell cancers. While the inactivation of VHL gene can be found in the majority of clear cell carcinomas, different molecular mechanisms are involved into...
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