Article
Association of a risk allele of ANK3 with cognitive performance and cortical thickness in patients with first-episode psychosis.
Journal of psychiatry & neuroscience : JPN - 1 Jan 2014
Cassidy Clifford, Buchy Lisa, Bodnar Michael, Dell'elce Jennifer, Choudhry Zia, Fathalli Ferid, Sengupta Sarojini, Fox Rebecca, Malla Ashok, Lepage Martin, Iyer Srividya, Joober Ridha
Abstract excerpt
BACKGROUND: The gene ANK3 is implicated in bipolar disorder and schizophrenia. The present study investigated the influence of this gene on cognitive performance and brain structure among individuals with first-episode psychosis (FEP). The brief illness duration of an FEP sample makes it well suited for studying the effects of genetic variation. METHODS: We genotyped 2 single nucleotide polymorphisms (SNPs;...
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