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Article

Variants in the IFNγ transcription factor genes TBET, STAT1, STAT4, and HLX and the risk of pulmonary tuberculosis in a Colombian population: a case-control study.

Biomedica : revista del Instituto Nacional de Salud - 1 Jan 2000

Sánchez Dulfary, Lefebvre Céline, García Luis F, Barrera Luis F

Abstract excerpt

INTRODUCTION: Interferon gamma (IFNγ) is the most potent cytokine involved in the control of Mycobacterium tuberculosis (Mtb), the etiological agent of human tuberculosis (TB). Patients with active TB present reduced levels of IFNγ, which may explain the lack of effective immunity against Mtb in...

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Source

Identifiers

PMID: 24652136

Genes

HLX
STAT1
STAT4
EMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24652136-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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