Article
Multilocus sequence typing of serially collected isolates of Cryptococcus from HIV-infected patients in South Africa.
Journal of clinical microbiology - 1 Jun 2014
Van Wyk Marelize, Govender Nelesh P, Mitchell Thomas G, Litvintseva Anastasia P
Abstract excerpt
Patients with cryptococcal meningitis in sub-Saharan Africa frequently relapse following treatment. The natural history and etiology of these recurrent episodes warrant investigation. Here, we used multilocus sequence typing (MLST) to compare the molecular genotypes of strains of Cryptococcus neo...
Topics
- Adolescent
- Adult
- Child
- Cluster Analysis
- Cryptococcus gattii
- Cryptococcus neoformans
- Female
- Genetic Variation
- Genotype
- HIV Infections
- Humans
- Longitudinal Studies
- Male
- Meningitis, Cryptococcal
- Middle Aged
- Multilocus Sequence Typing
- Recurrence
- South Africa