Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice.

PloS one - 1 Jan 2014

Huang Yuan, Caputo Christina R, Noordmans Gerda A, Yazdani Saleh, Monteiro Luiz Henrique, van den Born Jaap, van Goor Harry, Heeringa Peter, Korstanje Ron, Hillebrands Jan-Luuk

Abstract excerpt

A hallmark of aging-related organ deterioration is a dysregulated immune response characterized by pathologic leukocyte infiltration of affected tissues. Mechanisms and genes involved are as yet unknown. To identify genes associated with aging-related renal infiltration, we analyzed kidneys from aged mice (≥20 strains) for infiltrating leukocytes followed by Haplotype Association Mapping (HAM) analysis....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Ki-1 Antigen

Share to Kidney

Share to Lymphatic Vessels

Share to Lymphoid Tissue

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 24637805
DOI: 10.1371/journal.pone.0091850
PMCID: PMC3956762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of novel genes associated with renal tertiary lymphoid organ formation in aging mice.PMID 24637805Read ↗

Multi-omic and spatial analysis of mouse kidneys highlights sex-specific differences in gene regulation across the lifespanSemantic proximity Read ↗

Glomerular cell atlas of multi-disease model revealed the characteristic changes of glomerular cell subtypes in diseases.Semantic proximity Read ↗

A roadmap for the genetic analysis of renal aging.Semantic proximity Read ↗

Anatomical Transcriptome Atlas of the Male Mouse Reproductive System During AgingSemantic proximity Read ↗

Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomicsSemantic proximity Read ↗

Single-Cell Transcriptional Profiling Reveals Sex and Age Diversity of Gene Expression in Mouse Endothelial CellsSemantic proximity Read ↗

The aging kidney is characterized by tubuloinflammaging, a phenotype associated with MHC-II gene expression.Semantic proximity Read ↗

A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated macrophages in lupus nephritisSemantic proximity Read ↗

Ectopic lymphoid structures in the aged lacrimal glandsSemantic proximity Read ↗

Meta-Profiles of Gene Expression during Aging: Limited Similarities between Mouse and Human and an Unexpectedly Decreased Inflammatory SignatureSemantic proximity Read ↗

A single-cell transcriptomic landscape of mouse testicular agingSemantic proximity Read ↗

A Transcriptional Profile of Aging in the Human KidneySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.