Article
Genetic polymorphisms in glutathione-S-transferases are associated with anxiety and mood disorders in nicotine dependence.
Psychiatric genetics - 1 Jun 2014
Odebrecht Vargas Nunes Sandra, Pizzo de Castro Márcia Regina, Ehara Watanabe Maria Angelica, Losi Guembarovski Roberta, Odebrecht Vargas Heber, Reiche Edna Maria Vissoci, Kaminami Morimoto Helena, Dodd Seetal, Berk Michael
Abstract excerpt
BACKGROUND: Nicotine dependence is associated with an increased risk of mood and anxiety disorders and suicide. The primary hypothesis of this study was to identify whether the polymorphisms of two glutathione-S-transferase enzymes (GSTM1 and GSTT1 genes) predict an increased risk of mood and anxiety disorders in smokers with nicotine dependence. MATERIALS AND METHODS: Smokers were recruited at the Centre of...
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