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Article

Protein Kinase D as a Potential Chemotherapeutic Target for Colorectal Cancer

15 Mar 2014

Abstract excerpt

Protein kinase D (PKD) signaling plays a critical role in the regulation of DNA synthesis, proliferation, cell survival, adhesion, invasion/migration, motility, and angiogenesis. To date, relatively little is known about the potential role of PKD in the development and/or progression of human colorectal cancer. We evaluated the expression of different PKD isoforms in colorectal cancer and investigated the...

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PMID: 24634417
DOI: 10.1158/1535-7163.mct-13-0880

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