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Article

CD133+ tumor initiating cells in a syngenic murine model of pancreatic cancer respond to Minnelide.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2014

Banerjee Sulagna, Nomura Alice, Sangwan Veena, Chugh Rohit, Dudeja Vikas, Vickers Selwyn M, Saluja Ashok

Abstract excerpt

PURPOSE: Pancreatic adenocarcinoma is the fourth leading cause for cancer-related mortality with a survival rate of less than 5%. Late diagnosis and lack of effective chemotherapeutic regimen contribute to these grim survival statistics. Relapse of any tumor is largely attributed to the presence of tumor-initiating cells (TIC) or cancer stem cells (CSC). These cells are considered as hurdles to cancer therapy as...

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Identifiers

PMID: 24634377
DOI: 10.1158/1078-0432.CCR-13-2947
PMCID: PMC4008688

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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