Article
Modeling and testing for joint association using a genetic random field model.
Biometrics - 1 Sept 2014
He Zihuai, Zhang Min, Zhan Xiaowei, Lu Qing
Abstract excerpt
Substantial progress has been made in identifying single genetic variants predisposing to common complex diseases. Nonetheless, the genetic etiology of human diseases remains largely unknown. Human complex diseases are likely influenced by the joint effect of a large number of genetic variants instead of a single variant. The joint analysis of multiple genetic variants considering linkage disequilibrium (LD) and...
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