Article
Functional gene group analysis indicates no role for heterotrimeric G proteins in cognitive ability.
PloS one - 1 Jan 2014
Hill W David, de Leeuw Christiaan, Davies Gail, Liewald David Cherry McLachlan, Payton Anthony, Craig Leone C A, Whalley Lawrence J, Horan Mike, Ollier William, Starr John M, Pendleton Neil, Posthuma Danielle, Bates Timothy C, Deary Ian J
Abstract excerpt
Previous functional gene group analyses implicated common single nucleotide polymorphisms (SNPs) in heterotrimeric G protein coding genes as being associated with differences in human intelligence. Here, we sought to replicate this finding using five independent cohorts of older adults including current IQ and childhood IQ, and using both gene- and SNP-based analytic strategies. No significant associations were...
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