Article
Deregulation of COMMD1 is associated with poor prognosis in diffuse large B-cell lymphoma.
PloS one - 1 Jan 2014
Taskinen Minna, Louhimo Riku, Koivula Satu, Chen Ping, Rantanen Ville, Holte Harald, Delabie Jan, Karjalainen-Lindsberg Marja-Liisa, Björkholm Magnus, Fluge Øystein, Pedersen Lars Møller, Fjordén Karin, Jerkeman Mats, Eriksson Mikael, Hautaniemi Sampsa, Leppä Sirpa
Abstract excerpt
BACKGROUND: Despite improved survival for the patients with diffuse large B-cell lymphoma (DLBCL), the prognosis after relapse is poor. The aim was to identify molecular events that contribute to relapse and treatment resistance in DLBCL. METHODS: We analysed 51 prospectively collected pretreatment tumour samples from clinically high risk patients treated in a Nordic phase II study with dose-dense...
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