Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of estrogen beta and leptin receptors may cause gynecomastia in adolescent.

Gene - 15 May 2014

Eren Erdal, Edgunlu Tuba, Korkmaz Huseyin Anil, Cakir Esra Deniz Papatya, Demir Korcan, Cetin Esin Sakalli, Celik Sevim Karakas

Abstract excerpt

OBJECTIVE: Gynecomastia is a benign breast enlargement in males that affects approximately one-third of adolescents. The exact mechanism is not fully understood; however, it has been proposed that estrogen receptors and aromatase enzyme activity may play important roles in the pathogenesis of gynecomastia. While many studies have reported that aromatase enzyme (CYP19) gene polymorphism is associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aromatase
Share to Estradiol
Share to Estrogen Receptor beta

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Estrogens

Share to Gynecomastia

Share to Puberty

Share to Receptors, Leptin

Share to Testosterone

Source

Identifiers

PMID: 24625355
DOI: 10.1016/j.gene.2014.03.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of estrogen beta and leptin receptors may cause gynecomastia in adolescent.PMID 24625355Read ↗

Association between gynecomastia and aromatase (CYP19) polymorphisms.Semantic proximity Read ↗

GPR30 Gene Polymorphisms Are Associated with Gynecomastia Risk in Adolescents.Semantic proximity Read ↗

[Phenotype of patients with gynecomastia].Semantic proximity Read ↗

Aromatase excess syndrome: a rare autosomal dominant disorder leading to pre- or peri-pubertal onset gynecomastia.Semantic proximity Read ↗

A Novel Null Mutation in P450 Aromatase Gene (CYP19A1) Associated with Development of Hypoplastic Ovaries in HumansSemantic proximity Read ↗

Aromatase Deficiency due to a Novel Mutation in CYP19A1 GeneSemantic proximity Read ↗

Endocrine and molecular investigations in a cohort of 25 adolescent males with prominent/persistent pubertal gynecomastia.Semantic proximity Read ↗

Gene-wide association study between the aromatase gene (CYP19A1) and female pattern hair loss.Semantic proximity Read ↗

A Potential Rearrangement between CYP19 and TRPM7 Genes on Chromosome 15q21.2 as a Cause of Aromatase Excess SyndromeSemantic proximity Read ↗

Estrogen excess associated with novel gain-of-function mutations affecting the aromatase gene.Semantic proximity Read ↗

The Aromatase Cytochrome P-450 and Its Clinical ImpactSemantic proximity Read ↗

Novel CYP19A1 Mutations Extend the Genotype-Phenotype Correlation and Reveal the Impact on Ovarian FunctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.