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Article

A Potential Rearrangement between CYP19 and TRPM7 Genes on Chromosome 15q21.2 as a Cause of Aromatase Excess Syndrome

1 Jul 2005

Abstract excerpt

CONTEXT: Aromatase excess syndrome (AES) is a rare hereditary autosomal dominant disorder characterized by increased extraglandular aromatization of steroids and presented with heterosexual precocity in males and isosexual precocity in females. OBJECTIVE: The objective was to study the molecular basis of AES in a kindred with 16 affected subjects, both males and females. PATIENTS: The propositus, currently a...

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Identifiers

PMID: 15811932
DOI: 10.1210/jc.2004-2176

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