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HLA Identical (Related/Unrelated) Donor Hematopoietic Stem Cell Transplant for Hemoglobinopathies using Pre-transplant Immune Suppression and Post-transplant Cyclophosphamide: Does it Help Consolidate Our Gains?

2023-01-04

Abstract excerpt

<title>Abstract</title> <p>Awaiting gene therapy, hematopoietic stem cell transplant (HSCT) is only curative treatment for Transfusion Dependent Thalassemia (TDT)/Sickle Cell Disease (SCD). Although conventional myeloablative conditioning (MAB) with calcineurin inhibitor (CNI) based graft-versus-host-disease (GvHD) prophylaxis in HLA identical donors (related/unrelated) (MSD/MRD/MUD) have shown good outcomes but...

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Literature Corpus work
583a745d-6d81-5bb1-b074-4c7333ea326c
DOI
10.21203/rs.3.rs-2402457/v1
Open publication

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HLA Identical (Related/Unrelated) Donor Hematopoietic Stem Cell Transplant for Hemoglobinopathies using Pre-transplant Immune Suppression and Post-transplant Cyclophosphamide: Does it Help Consolidate Our Gains?DOI 10.21203/rs.3.rs-2402457/v1
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