Article
Association of BH3 interacting domain death agonist (BID) gene polymorphisms with proteinuria of immunoglobulin A nephropathy.
Scandinavian journal of clinical and laboratory investigation - 1 Jun 2014
Park Hae Jeong, Kim Jong Woo, Cho Byoung-Soo, Chung Joo-Ho
Abstract excerpt
BACKGROUND: Apoptosis plays an important role in the mechanism regulating the development of glomerulonephritis. We investigated whether polymorphisms of apoptotic genes such as B-cell CLL/lymphoma 2 (BCL2), BH3-interacting domain death agonist (BID), and caspase 8 (CASP8) were associated with immunoglobulin A nephropathy (IgAN) and with the clinical phenotypes of IgAN patients. METHODS: We genotyped promoter and...
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