NOBOX is a key FOXL2 partner involved in ovarian folliculogenesis

Abstract excerpt

Dear Editor, Early ovarian expression of Newborn oogenesis homeobox (NOBOX), a transcription factor belonging to the homeoprotein class, is decisive for the progression of primordial follicles to the primary follicular stage as demonstrated by the sterility of Nobox−/− female mice (Rajkovic et al., 2004). Consequently, the loss of the Nobox gene causes primary ovarian insufficiency (POI) (Rajkovic et al., 2004)...

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