Article
A Novel Functional Role for the Oocyte-Specific Transcription Factor Newborn Ovary Homeobox (NOBOX) during Early Embryonic Development in Cattle
31 Dec 2010
Abstract excerpt
Newborn ovary homeobox (NOBOX) is an oocyte-specific transcription factor essential for folliculogenesis and expression of many germ cell-specific genes in mice. Here we report the characterization of the bovine NOBOX gene and its role in early embryogenesis. The cloned cDNA for bovine NOBOX contains an open reading frame encoding a protein of 500 amino acids with a conserved homeodomain. mRNA for NOBOX is...
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