Article
Impact of methylenetetrahydrofolate reductase C677T polymorphism on the risk of gastric cancer and its interaction with Helicobacter pylori infection.
Iranian biomedical journal - 1 Jan 2012
Saberi Samaneh, Zendehdel Kazem, Jahangiri Sahar, Talebkhan Yeganeh, Abdirad Afshin, Mohajerani Nazanin, Bababeik Maryam, Karami Najmeh, Esmaili Maryam, Oghalaie Akbar, Hassanpour Parisa, Amini Neda, Mohagheghi Mohammad Ali, Eshagh Hossieni Mahmoud, Mohammadi Marjan
Abstract excerpt
BACKGROUND: Attempts for early detection of gastric cancer have recently focused on host's genetic susceptibility factors and gene-environment interactions. We have, herein, studied the association of MTHFR C677T single nucleotide polymorphism (SNP) and its interaction with Helicobacter pylori infection, smoking, age and gender on the risk of gastric cancer among an Iranian population. METHODS: Gastric cancer...
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