Article
The protein phosphatase PhzA of A. fumigatus is involved in oxidative stress tolerance and fungal virulence.
Fungal genetics and biology : FG & B - 1 May 2014
Muszkieta Laetitia, Carrion Steven de Jesus, Robinet Pauline, Beau Rémi, Elbim Carole, Pearlman Eric, Latgé Jean-Paul
Abstract excerpt
Protein phosphatases Z that are unique to the fungal kingdom have been associated to resistance to high salt concentration, cell wall integrity, cell cycle regulation, and oxidative stress in fungi. In Aspergillus fumigatus, it was shown that PHZA is under the control of the transcription factor Skn7 and is only involved in the control of the oxidative stress. Accordingly, the ΔphzA mutant showed a defect in...
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