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Article

Immunohistochemistry as a screening tool for ALK rearrangement in NSCLC: evaluation of five different ALK antibody clones and ALK FISH.

Histopathology - 1 Sept 2014

Hutarew Georg, Hauser-Kronberger Cornelia, Strasser Felix, Llenos Ida C, Dietze Otto

Abstract excerpt

AIMS: ALK FISH analysis is used as the reference standard to demonstrate ALK rearrangements, which qualify patients with pulmonary adenocarcinomas for therapy with ALK inhibitors. The aim of this study was to find screening ALK antibody clones with the best positive and best negative percentage agreement with ALK FISH. METHODS AND RESULTS: Three hundred and three pulmonary adenocarcinomas were evaluated with ALK...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24612196
DOI: 10.1111/his.12399

Genes

ALK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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