Article
Stepwise metabolic adaption from pure metabolization to balanced anaerobic growth on xylose explored for recombinant Saccharomyces cerevisiae.
Microbial cell factories - 8 Mar 2014
Klimacek Mario, Kirl Elisabeth, Krahulec Stefan, Longus Karin, Novy Vera, Nidetzky Bernd
Abstract excerpt
BACKGROUND: To effectively convert lignocellulosic feedstocks to bio-ethanol anaerobic growth on xylose constitutes an essential trait that Saccharomyces cerevisiae strains normally do not adopt through the selective integration of a xylose assimilation route as the rate of ATP-formation is below energy requirements for cell maintenance (mATP). To enable cell growth extensive evolutionary and/or elaborate...
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