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Article

Cystatin C is differentially involved in multiple system atrophy phenotypes.

Neuropathology and applied neurobiology - 1 Jun 2015

Urbizu Aintzane, Canet-Pons Julia, Munoz-Marmol Ana M, Aldecoa Iban, Lopez Maria T, Compta Yaroslau, Alvarez Ramiro, Ispierto Lourdes, Tolosa Eduardo, Ariza Aurelio, Beyer Katrin

Abstract excerpt

AIMS: As cystatin C (CysC) is involved in some forms of neurodegeneration, we investigated the possible relationship between CysC and multiple system atrophy (MSA), including its parkinsonian (MSAp) and cerebellar (MSAc) phenotypes. METHODS: Cystatin C gene (CST3) haplotypes were determined by PCR followed by KspI digestion in 50 MSA patients and 108 controls. CST3 and cathepsins B, D and L1 mRNA levels were...

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Source

Identifiers

PMID: 24606172
DOI: 10.1111/nan.12134

Genes

CST3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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