Article
Endothelial cells promote stem-like phenotype of glioma cells through activating the Hedgehog pathway.
The Journal of pathology - 1 Sept 2014
Yan Guang-Ning, Yang Lang, Lv Yang-Fan, Shi Yu, Shen Li-Li, Yao Xiao-Hong, Guo Qiao-Nan, Zhang Peng, Cui You-Hong, Zhang Xia, Bian Xiu-Wu, Guo De-Yu
Abstract excerpt
Microenvironmental regulation of cancer stem cells (CSCs) strongly influences the onset and spread of cancer. The way in which glioma cells interact with their microenvironment and acquire the phenotypes of CSCs remains elusive. We investigated how communication between vascular endothelial cells...
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