Article
Epigenetics decouples mutational from environmental robustness. Did it also facilitate multicellularity?
PLoS computational biology - 1 Mar 2014
Gombar Saurabh, MacCarthy Thomas, Bergman Aviv
Abstract excerpt
The evolution of ever increasing complex life forms has required innovations at the molecular level in order to overcome existing barriers. For example, evolving processes for cell differentiation, such as epigenetic mechanisms, facilitated the transition to multicellularity. At the same time, studies using gene regulatory network models, and corroborated in single-celled model organisms, have shown that...
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