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Article

Porphyromonas gingivalis and Treponema denticola Exhibit Metabolic Symbioses

6 Mar 2014

Abstract excerpt

Porphyromonas gingivalis and Treponema denticola are strongly associated with chronic periodontitis. These bacteria have been co-localized in subgingival plaque and demonstrated to exhibit symbiosis in growth in vitro and synergistic virulence upon co-infection in animal models of disease. Here we show that during continuous co-culture a P. gingivalis:T. denticola cell ratio of 6∶1 was maintained with a...

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PMID: 24603978
DOI: 10.1371/journal.ppat.1003955

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