Article
Hemagglutinin/Adhesin domains ofPorphyromonas gingivalisplay key roles in coaggregation withTreponema denticola
13 Sept 2010
Abstract excerpt
Porphyromonas gingivalis and Treponema denticola are major pathogens of periodontal disease. Coaggregation between microorganisms plays a key role in the colonization of the gingival crevice and the organization of periodontopathic biofilms. We investigated the involvement of surface ligands of P. gingivalis in coaggregation. Two triple mutants of P. gingivalis lacking Arg-gingipain A (RgpA), Lys-gingipain (Kgp)...
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