Article
[Applications of microchip electrophoresis and capillary electrophoresis for screening FLT3-ITD gene mutation in acute myeloid leukemia].
Zhongguo shi yan xue ye xue za zhi - 1 Feb 2014
Leng Xin, Li Ling-Di, Li Jin-Lan, Huang Xiao-Jun, Ruan Guo-Rui
Abstract excerpt
The purpose of the present study was to compare the reliability of microchip electrophoresis and capillary electrophoresis for screening FLT3-ITD gene mutation in acute myeloid leukemia. The FLT3-ITD mutation in the genomic DNA samples from 214 untreated AML patients were separately detected by PCR-microchip electrophoresis and PCR-capillary electrophoresis, then the DNA direct sequencing analysis was carried...
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