Article
Does APOE genotype modify the relations between serum lipid and erythrocyte omega-3 fatty acid levels?
Journal of cardiovascular translational research - 1 Jul 2014
Harris William S, Pottala James V, Thiselton Dawn L, A Varvel Stephen, Baedke Alison M, Dayspring Thomas D, Warnick G Russell, McConnell Joseph P
Abstract excerpt
Earlier reports indicated that patients with the apolipoprotein APOE ε4 allele responded to fish oil supplementation with a rise in serum low-density lipoprotein cholesterol (LDL-C) compared to ε3 homozygotes. In this study, we used clinical laboratory data to test the hypothesis that the cross-sectional relation between RBC omega-3 fatty acid status (the Omega-3 Index) and LDL-C was modified by APOE genotype....
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