Article
Disrupted fatty acid distribution in HDL and LDL according to apolipoprotein E allele.
Nutrition (Burbank, Los Angeles County, Calif.) - 1 Jun 2015
Dang Thuy Mai, Conway Valérie, Plourde Mélanie
Abstract excerpt
OBJECTIVES: Omega-3 polyunsaturated fatty acid (ω-3 PUFA) metabolism seems to be disrupted in carriers of the epsilon 4 allele of apolipoprotein E (E4+). The objective of this study was to investigate whether the ω-3 PUFA distribution in the high and low density lipoproteins is APOE-genotype dependant before and after supplementation with ω-3 PUFAs. METHODS: Eighty participants, aged between 20 and 35 y old were...
Topics
- Adult
- Alleles
- Apolipoproteins E
- Atherosclerosis
- Dietary Supplements
- Docosahexaenoic Acids
- Fatty Acids, Omega-3
- Fatty Acids, Omega-6
- Female
- Genotype
- Humans