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Article

Polymorphisms in radio-responsive genes and its association with acute toxicity among head and neck cancer patients.

PloS one - 1 Jan 2014

Venkatesh Goutham Hassan, Manjunath Vadhiraja Bejadi, Mumbrekar Kamalesh Dattaram, Negi Hitendra, Fernandes Donald Jerard, Sharan Krishna, Banerjee Sourjya, Bola Sadashiva Satish Rao

Abstract excerpt

Cellular and molecular approaches are being explored to find a biomarker which can predict the development of radiation induced acute toxicity prior to radiation therapy. SNPs in radiation responsive genes may be considered as an approach to develop tools for finding the inherited basis of clinical radiosensitivity. The current study attempts to screen single nucleotide polymorphisms/deletions in DNA damage...

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Share to Chemoradiotherapy
Share to Confounding Factors, Epidemiologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Association Studies

Share to Head and Neck Neoplasms

Share to Linkage Disequilibrium

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Source

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Identifiers

PMID: 24594932
DOI: 10.1371/journal.pone.0089079
PMCID: PMC3942321

Genes

NBN
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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